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Although the adult liver is composed primarily of hepatocytes (80%), it is heterogenous with other types of cells present (endothelial, biliary and stellate cells) (Usynin and Panin, 2008

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(34) The isodesmic method relies on the experimentally determined p K a of a reference acid (p K a ref ) to compute the p K a through eq 2: (3841) R is the general gas constant, and T is the temperature