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doi: 10.1001/jama.1995.03530130055028 47

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For example, somewhat optimistic results were described in a subset of pivotal trials (Phase 2 and 3 trials in support of drug/biologic approval) studied by Eshera et al

Of course, it is unwise to directly compare the doses given to animals and the doses given to humans, as the bodys surface area should also be taken into account when translating doses between species

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