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Astrocytic downregulation of GLAST elevates synaptic glutamate (Glu), activating neuronal N-methyl-d-aspartic acid receptor (NMDA) receptors to induce calcium influx and mitochondrial ROS bursts (OH), indirectly triggering pyroptosis [58]
10.1038/s41420-021-00625-7 134 WangZ.SunY.YaoW.BaQ.WangH
Thus, it appears that l-theanine acts on sleep through anxiolytic and not hypnotic effects [65]
