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Whereas the rough microsomes tend to be dedicated to protein synthesis, the smooth microsomes are relatively rich in enzymes responsible for oxidative drug metabolism
The mechanism of action has been determined that KPV inhibits the activation of NF-kappaB and MAP kinase inflammatory signaling pathways, and reduces pro-inflammatory cytokine secretionacts via PepT1 expressed in immune and intestinal epithelial cells..[and] reduces the incidence of DSS- and TNBS-induced colitis indicated by a decrease in pro-inflammatory cytokine expression (Dalmasso et al., 2008)
Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats
Plant Sci 318:111237
