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However, if modified (PEGylation or ligand-functionalization), PLGA nanoparticles could escape the RES clearance, allowing longer systemic plasma half-life and accumulation in the CNS 99

Sakai D, Nakai T, Mochida J, Alini M, Grad S: Differential phenotype of intervertebral disc cells: microarray and immunohistochemical analysis of canine nucleus pulposus and anulus fibrosus

Research indicates that both intramuscular and high-dose oral vitamin B12 are effective in normalizing serum levels and improving clinical outcomes
I just cannot bring myself to get the vaccine knowing that many are suffering from debilitating immediate side effects and we dont know the long term potential for health problems associated with these experimental vaccines
