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Common symptoms include epilepsy, developmental regression, and ophthalmologic abnormalities

These studies highlighted a potential mechanism by which SCs can actively modulate the local environment by influencing the biosynthesis of ECM components, further avoiding an excessive deposition of collagen during muscle adaptive responses (Figure 1b, lower panel)

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doi: 10.3390/biomedicines9091206 Seiwerth S, Milavic M, Vukojevic J, et al
J Natl Cancer Inst (2014) 106(6):dju124