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Given the central role of oxidative stress in both acute injury and long-term remodeling, modulation of redox pathways represents a critical therapeutic objective (43)

549 Serine palmitoyltransferase (SPT) is critical for sphingomyelin biosynthesis

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doi: 10.1056/NEJMoa1310460 254 FariesMBThompsonJFCochranAJAndtbackaRHMozzilloNZagerJSet al