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Ascorbic acid stimulates DOPA synthesis and tyrosine hydroxylase gene expression in the human neuroblastoma cell line SK-N-SH

In recent studies using BRET (Bioluminescence Resonance Energy Transfert) or FRET (Fluorescence Resonance Energy Transfer) techniques, a large panel of opioid ligands were shown to have a different ability to both activate G proteins and recruit arrestins at MOR and DOR (Mcpherson et al., 2010
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doi: 10.1016/B978-0-12-804766-8.00013-3

To validate these findings in vivo, we assessed lipolysis in AAV-shRNA-mediated Gpr146 knockdown mice following stimulation with CL316,243, a 3-adrenergic receptor agonist
