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It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]

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KPV inhibitsNF-B activation at nanomolar concentrations through stabilization of IB- and prevention of p65RelA nuclear translocation[13]
Carbonate radicals react with target molecules either by hydrogen abstraction or by electron transfer (Samuni et al

20,189 Copper chelators have also been shown to enhance the effectiveness of immune cells such as CD8 + T cells and natural killer (NK) cells in the tumor microenvironment (TME), thereby slowing tumor growth and improving survival rates in mice
