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It is characterized by microglial activation and enhanced release of inflammatory factors, such as tumor necrosis factor (TNF-), IL-2, IL-10, IL-4, IL-6, and interferon , which contribute to neuronal injury and death [30, 31]

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" Clin Infect Dis

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KPV inhibitsNF-B activation at nanomolar concentrations through stabilization of IB- and prevention of p65RelA nuclear translocation[13]

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Carbonate radicals react with target molecules either by hydrogen abstraction or by electron transfer (Samuni et al

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20,189 Copper chelators have also been shown to enhance the effectiveness of immune cells such as CD8 + T cells and natural killer (NK) cells in the tumor microenvironment (TME), thereby slowing tumor growth and improving survival rates in mice

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