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This process is catalyzed primarily by the same UGT1A1 enzyme on the endoplasmic reticulum, although a second enzyme, located in the canalicular portion of the hepatocyte plasma cell membrane, UDP-glucuronate glucuronosyltransferase (transglucuronidase), may also play a role

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doi:10.1002/asia.201700814 33

Tilt the vial slightly so the needle tip touches the inside wall of the vial, near the glass

This is when the tissue starts to regain actual load-bearing capacity