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Potential disease mechanisms of brain toxicity include toxic effects of excess or deficiency of intermediates in the carnitine biosynthetic pathway or carnitine deficiency in early stages of life during brain development in which the availability of carnitine/acetylcarnitine might affect gene transcription or neurotransmitters balance [169]

Consequently, targeted educational initiatives and improved access to qualified healthcare services may play a critical role in effective prevention and harm-reduction strategies (46, 47)

Bernard Knapp, pp
Epidemiology of depressive disorders in patients with liver cirrhosis: a population-based study in the United States
