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Drugs Today 55, 1723

Hidaka H, Nakazawa T, Kutsukake S, et al

After completion of biosynthesis, secondary metabolites like GSLs and flavonoids, which are present at high concentrations in the cell, need to be imported into the vacuole ( Figure 2 , the identity is unknown), stored there or further metabolized and/or transported ( Figure 3 , transporters 16 and 17)

In addition, multifunctional nanoparticles HA/AIPH@ZIF-8 (HAZ) containing hyaluronic acid where dsDNA and zeolitic imidazolate framework (ZIF-8)-derived zinc ions can promote the STING pathway, and mediate DCs maturation and CTLs infiltration through ICD thereby enhancing tumor immunotherapy (205)

Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart