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The effects of ferroptosis include membrane destabilization, mitochondrial dysfunction, cytoskeletal rearrangements, and the impairment of protein degradation, all of which are detrimental to the cell (Fig

However, we did not have information of the disease severity at the sampling time (Supplementary Table 6, Fig

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Other risk factors are obesity and high caloric intake

We took into account confounding factors including age, gender, physical activity level, occupation, education level, and place of residence