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In: Tihanyi K, Vastag M, editors

For example, opioids decrease pulmonary perfusion via hypoxia-induced pulmonary vasoconstriction 143 , and by direct pulmonary vasoconstriction 144,145 by mechanisms including centrally-mediated activation of sympathetic nerve activity to the lungs 146 , and induction of histamine release in the lungs 144,147

Furthermore, ~70% of individuals with T2D are concurrently diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD)

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