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Thus, the identified proteins in this study might represent a target of responsiveness for hCG stimulation on sperm quality and fertility outcomes

Ethics statement Ethical approval was not required for the studies on humans in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used

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An experiment in flies showed that increased electron influx and continuous electron flow through the ETC can activate ROS-RET signaling in mitochondria, generating NADPH for reductive and anabolic processes, ultimately extending lifespan under basal conditions [111]