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Research has shown that a high-fat diet decreases GABA levels in the frontal cortex and hippocampus, which likely disrupts the GABAergic inhibitory processes and may explain feeding behavior

[DOI] [PubMed] [Google Scholar] 15
Diet, sleep, and pollution exposure all influence how much antioxidant support your body actually needs

The usual timeline Reports describe tiredness starting in the first week to 1 to 2 weeks after beginning treatment, with improvement over the next 2 to 4 weeks as the body adapts, according to this overview on when Lexapro fatigue starts and improves

M.BrownR
