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MACE: major adverse cardiovascular event

Multiple NIH institutes, including NIAAA and NIDA, have invested tens of millions in clinical trials studying GLP-1 receptor agonists for substance use disorders, including alcohol addiction
Its primary physiological functions include promoting glucose-dependent insulin secretion, enhancing hepatic glycogen synthesis, and increasing the buffering capacity of adipose tissue for lipids

Hyperglycemia induces NF-kappaB activation and MCP-1 expression via downregulating GLP-1R expression in rat mesangial cells: inhibition by metformin

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