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Emanuel, Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity

GIP agonism GIP is secreted by K-cells in jejunum in response to food intake and its physiological role includes stimulation of insulin secretion, increased glucagon secretion, increased lipogenesis and enhancement of lipid buffering capacity (Fig

Ethical Considerations This study (ICREC#7363051) was reviewed by the Imperial College Research Ethics Committee, which granted a favorable opinion, signifying that the Committee determined the study to be ethically acceptable and in alignment with institutional and regulatory guidelines

Riley MG, Castelli MC, Paehler EA

Most people notice appetite suppression within days, sometimes within hours of the first dose