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Maintaining adequate protein intake throughout the program is the most important protective factor, and nutritional monitoring is part of how we manage this

Contraindicated in personal/family medullary thyroid cancer or MEN2 syndrome

Current Safety Evidence: What Clinical Trials and Real-World Data Tell Us Semaglutide's long-term safety profile comes primarily from the SUSTAIN clinical trial series (up to 2 years) and post-marketing pharmacovigilance

That said, higher efficacy came with higher side-effect and discontinuation rates, reinforcing an important point: 1

Medications like Ozempic, Wegovy, and Mounjaro are GLP-1 receptor agonists