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state and territory attorney generals wrote the FDA seeking action against illegally sold weight-loss medicines, including "research purposes only" ingredients from China

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The Phase 2 NEJM trial (2023) Published in the New England Journal of Medicine under the title "Triple-Hormone-Receptor Agonist Retatrutide for Obesity," this trial (NCT04881760) enrolled 338 adults and ran for 48 weeks

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Good prescribers discuss ranges, set realistic expectations, and emphasize that results depend on medication plus lifestyle modification

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Regardless, one of these medications may be effective for individuals and their weight loss journey

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