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Participants receiving 2.4 mg of Sema weekly, alongside lifestyle modifications, experienced an average 14.9% reduction in body weight over 68 weekssubstantially more than the placebo group

7376 Table 2 summarizes the key studies, their populations, and main findings

[DOI] [PubMed] [Google Scholar] [18].Kieffer TJ, McIntosh CH, Pederson RA, Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV, Endocrinology, 136 (1995) 35853596

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These findings suggest improved mitochondrial energetics and redox regulation within immune and vascular compartments