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Ungewiss, K
[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Santoro A, McGraw TE, and Kahn BB, Insulin Action in Adipocytes, Adipose Remodeling, and Systemic Effects, Cell Metabolism 33, no

It remains in active Phase 3 development, with Eli Lilly targeting an NDA filing later in 2026 based on the TRIUMPH-1 and TRIUMPH-4 data reported so far

This protein is projected from the NTS to the BLA, where it enhances c-Fos expression in glutamatergic neurons

And of course, the weight loss many patients experience can also improve lung function and reduce asthma severity, so its likely a combination of these effects working together. Snyder said more research is needed to confirm the effects in people who are not obese
