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Intrathecal injection of exendin-4 reduced pain sensitivity as assessed by the von Frey test and decreased neuroinflammation, with reduced TNF, IL-1 and IL-6 levels, thus demonstrating that analgesic effects of GLP-1R signalling were directly correlated with its anti-neuroinflammation activity [89]

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Under its new policy, Blue Cross Blue Shield of Massachusetts said Thursday it will continue to cover the meds, known as GLP-1s, in its standard health benefits when theyre prescribed for diabetes but not for obesity

This condition, called dilutional hyponatremia, causes the exact same symptoms people are trying to fix: headaches, fatigue, nausea, and confusion